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The mean projected daily acyclovir exposures in pediatric patients across all age-groups (1 to <12 years of age) were lower (C max: ↓13%, vytorin uk AUC: ↓30%) than the mean daily historical exposures in adults receiving valacyclovir 1 gram 3 times daily, but were higher (daily AUC: ↑50%) than the mean daily historical exposures in adults receiving acyclovir 800 mg 5 times daily.